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Article

Hydroxylation index of omeprazole in relation to CYP2C19 polymorphism and sex in a healthy Iranian population.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences - 11 Dec 2014

Payan Maryam, Rouini Mohammad Reza, Tajik Nader, Ghahremani Mohammad Hossein, Tahvilian Reza

Abstract excerpt

BACKGROUND: Polymorphism of CYP2C19 gene is one of the important factors in pharmacokinetics of CYP2C19 substrates. Omeprazole is a proton pump inhibitor which is mainly metabolized by cytochrome P450 2C19 (CYP2C19). The aim of present study was to assess omeprazole hydroxylation index as a measure of CYP2C19 activity considering new variant allele (CYP2C19*17) in Iranian population and also to see if this...

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Identifiers

PMID: 25498969
DOI: 10.1186/s40199-014-0081-6
PMCID: PMC4266903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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