Article
Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy.
Epilepsia - 1 Apr 2007
Soranzo Nicole, Kelly Libusha, Martinian Lillian, Burley Mari-Wyn, Thom Maria, Sali Andrej, Kroetz Deanna L, Goldstein David B, Sisodiya Sanjay M
Abstract excerpt
BACKGROUND: Multidrug transporters are postulated to contribute to antiepileptic drug (AED) resistance. The transporter best studied is P-glycoprotein, an ATP-Binding Cassette (ABC) transporter superfamily member. RLIP76 is suggested to be an energy-dependent non-ABC transporter, reducing AED blo...
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