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Article

A crucial role for Olig2 in white matter astrocyte development.

Development (Cambridge, England) - 1 May 2007

Cai Jeff, Chen Ying, Cai Wen-Hui, Hurlock Edward C, Wu Heng, Kernie Steven G, Parada Luis F, Lu Q Richard

Abstract excerpt

The mechanisms underlying astrocyte heterogeneity in the developing mouse brain are poorly understood. The bHLH transcription factor Olig2 is essential for motoneuron and oligodendrocyte formation; however, its role in astrocyte development remains obscure. During cortical development, Olig2 is transiently expressed in immature developing astrocytes at neonatal stages and is progressively downregulated in...

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PMID: 17428828
DOI: 10.1242/dev.02847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A crucial role for Olig2 in white matter astrocyte development.PMID 17428828Read ↗

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