Article
Olig1 function is required for oligodendrocyte differentiation in the mouse brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Mar 2015
Dai Jinxiang, Bercury Kathryn K, Ahrendsen Jared T, Macklin Wendy B
Abstract excerpt
Oligodendrocyte differentiation and myelination are tightly regulated processes orchestrated by a complex transcriptional network. Two bHLH transcription factors in this network, Olig1 and Olig2, are expressed exclusively by oligodendrocytes after late embryonic development. Although the role of Olig2 in the lineage is well established, the role of Olig1 is still unclear. The current studies analyzed the function...
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