Article
Strong association of interleukin-4 (-590 C/T) polymorphism with increased risk for oral squamous cell carcinoma in Europeans.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics - 1 Dec 2007
Vairaktaris Eleftherios, Yannopoulos Athanasios, Vassiliou Stavros, Serefoglou Zoe, Vylliotis Antonis, Nkenke Emeka, Critselis Elena, Avgoustidis Dimitrios, Yapijakis Christos, Neukam Friedrich W, Patsouris Efstratios
Abstract excerpt
OBJECTIVE: The present study was performed to investigate the possible association of -590 C/T polymorphism in the interleukin-4 (IL-4) gene which affects its expression with the risk for development of oral cancer. STUDY DESIGN: Polymerase chain reaction-based restriction analysis was performed in DNA samples of 156 patients with oral squamous cell carcinoma (OSCC) and 162 healthy control subjects of equivalent...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Carcinoma, Squamous Cell
- Case-Control Studies
- Female
- Humans
- Interleukin-4
- Male