Article
Progress in defining the genetic contribution to type 2 diabetes susceptibility.
Current opinion in genetics & development - 1 Jun 2018
Morris Andrew P
Abstract excerpt
Candidate gene, genome-wide association, exome array and sequencing studies have identified more than 140 loci associated with type 2 diabetes (T2D) susceptibility. In this review, progress in understanding the genetic architecture of T2D susceptibility across diverse populations and in localising potential causal variants for the disease through fine-mapping studies is discussed. The additional insights gained...
Topics
- Diabetes Mellitus, Type 2
- Genetic Loci
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Polymorphism, Single Nucleotide