Article
Association of IL10 promoter polymorphism in Italian Alzheimer's disease.
Neuroscience letters - 18 May 2007
Bagnoli Silvia, Cellini Elena, Tedde Andrea, Nacmias Benedetta, Piacentini Silvia, Bessi Valentina, Bracco Laura, Sorbi Sandro
Abstract excerpt
Recent studies have reported a genetic association between single nucleotide polymorphisms (SNPs) in the promoter region of Interleukin (IL) 10 and Alzheimer's disease (AD) with conflicting results. To further investigate the proposed association and to clarify the role of cytokines as a potential cause for AD susceptibility, we analyzed genotypes, allele distributions and haplotypes of IL10 promoter...
Topics
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Interleukin-10
- Italy
- Male
