Article
Toward ribosomal RNA catalytic activity in the absence of protein.
Journal of molecular evolution - 1 Apr 2007
Anderson Rachel M, Kwon Miyun, Strobel Scott A
Abstract excerpt
The ribosome is the ribonucleoprotein particle responsible for translation of genetic information into proteins. The RNA component of the ribosome has been implicated as the catalytic entity for peptide bond formation based on protease resistance and structural data indicating an all-RNA active site. Nevertheless, peptidyl transfer by ribosomal RNA (rRNA) alone has not been demonstrated. In an attempt to show...
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