Article
A unified model for functional and statistical epistasis and its application in quantitative trait Loci analysis.
Genetics - 1 Jun 2007
Alvarez-Castro José M, Carlborg Orjan
Abstract excerpt
Interaction between genes, or epistasis, is found to be common and it is a key concept for understanding adaptation and evolution of natural populations, response to selection in breeding programs, and determination of complex disease. Currently, two independent classes of models are used to study epistasis. Statistical models focus on maintaining desired statistical properties for detection and estimation of...
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