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Article

Epistasis and its contribution to genetic variance components.

Genetics - 1 Mar 1995

Cheverud J M, Routman E J

Abstract excerpt

We present a new parameterization of physiological epistasis that allows the measurement of epistasis separate from its effects on the interaction (epistatic) genetic variance component. Epistasis is the deviation of two-locus genotypic values from the sum of the contributing single-locus genotypic values. This parameterization leads to statistical tests for epistasis given estimates of two-locus genotypic values...

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Identifiers

PMID: 7768453
DOI: 10.1093/genetics/139.3.1455
PMCID: PMC1206471

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