Article
How to perform meaningful estimates of genetic effects.
PLoS genetics - 2 May 2008
Alvarez-Castro José M, Le Rouzic Arnaud, Carlborg Orjan
Abstract excerpt
Although the genotype-phenotype map plays a central role both in Quantitative and Evolutionary Genetics, the formalization of a completely general and satisfactory model of genetic effects, particularly accounting for epistasis, remains a theoretical challenge. Here, we use a two-locus genetic system in simulated populations with epistasis to show the convenience of using a recently developed model, NOIA, to...
Topics
- Animals
- Chickens
- Crosses, Genetic
- Databases, Genetic
- Epistasis, Genetic
- Female
- Genotype
- Male
- Models, Genetic
- Models, Statistical
- Phenotype
- Quantitative Trait Loci
- Regression Analysis