Article
Transcription of the 1.688 satellite DNA family is under the control of RNA interference machinery in Drosophila melanogaster ovaries.
Genetics - 1 Jun 2007
Usakin Lev, Abad José, Vagin Vasily V, de Pablos Beatriz, Villasante Alfredo, Gvozdev Vladimir A
Abstract excerpt
Here we show that RNA interference (RNAi) machinery operates in Drosophila melanogaster 1.688 satellite transcription. Mutation in the spn-E gene, known to be involved in RNAi in the oocytes, causes an increase of satellite transcript abundance. Transcripts of both strands of 1.688 satellite repeats in germinal tissues were detected. The strength of the effects of the spn-E mutation differs for 1.688 satellite...
Topics
- Animals
- Chromatin
- Cloning, Molecular
- DNA Primers
- DNA, Satellite
- Drosophila melanogaster
- Female
- Mutation
- Oocytes
- Ovary
- RNA Interference