Article

Cross-species incompatibility between a DNA satellite and the Drosophila Spartan homolog poisons germline genome integrity

2021-08-13

Abstract excerpt

<h4>ABSTRACT</h4> Satellite DNA spans megabases of eukaryotic sequence and evolves rapidly. Paradoxically, satellite-rich genomic regions mediate strictly conserved, essential processes like chromosome segregation and nuclear structure. A leading resolution to this paradox posits that satellite DNA and satellite-associated chromosomal proteins coevolve to preserve these essential functions. We experimentally test...

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Literature Corpus work: 27930a9c-8e36-5f83-b81b-d9f4635d4453
DOI: 10.1101/2021.08.13.455988

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