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Article

Anaemia characterises patients with myelofibrosis harbouring Mpl mutation.

British journal of haematology - 1 May 2007

Guglielmelli Paola, Pancrazzi Alessandro, Bergamaschi Gaetano, Rosti Vittorio, Villani Laura, Antonioli Elisabetta, Bosi Alberto, Barosi Giovanni, Vannucchi Alessandro M

Abstract excerpt

The clinical and haematological phenotype of patients with myelofibrosis harbouring MPL(W515L/K) mutation has not been thoroughly investigated. Of 217 myelofibrosis subjects, 18 (8.2%) had an MPL mutation, four of which (22%) co-existed with JAK2(V617F) mutation. When compared with MPL wild-type patients, irrespective of JAK2(V617F) status, those with MPL(W515L/K), were more frequently female, were older (61...

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Source

Identifiers

PMID: 17408465
DOI: 10.1111/j.1365-2141.2007.06565.x

Genes

MPL
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Anaemia characterises patients with myelofibrosis harbouring Mpl mutation.PMID 17408465Read ↗

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