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Article

Molecular genetics of the platelet serotonin system in first-degree relatives of patients with autism.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2008

Cross Sarah, Kim Soo-Jeong, Weiss Lauren A, Delahanty Ryan J, Sutcliffe James S, Leventhal Bennett L, Cook Edwin H, Veenstra-Vanderweele Jeremy

Abstract excerpt

Elevated platelet serotonin (5-hydroxytryptamine, 5-HT) is found in a subset of children with autism and in some of their first-degree relatives. Indices of the platelet serotonin system, including whole blood 5-HT, 5-HT binding affinity for the serotonin transporter (K(m)), 5-HT uptake (V(max)), and lysergic acid diethylamide (LSD) receptor binding, were previously studied in 24 first-degree relatives of...

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Source

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Identifiers

PMID: 17406648
DOI: 10.1038/sj.npp.1301406
PMCID: PMC2739682

Genes

TPH1
HTR7
ITGB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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