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Article

Hyperserotonemia in autism: the potential role of 5HT-related gene variants.

Collegium antropologicum - 1 Jan 2008

Hranilović Dubravka, Novak Ruder, Babić Marina, Novokmet Mislav, Bujas-Petković Zorana, Jernej Branimir

Abstract excerpt

Increased platelet serotonin level (PSL) has been consistently found in a portion of autistic patients. Suggested mechanisms for hyperserotonemia in autism have been increased synthesis of serotonin (5HT) by tryptophan hydroxylase (TPH), increased uptake into platelets through 5HT transporter (5HTt), diminished release from platelets through 5HT2A receptor (5HT2Ar) and decreased metabolism by monoamine oxydase...

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Share to Autistic Disorder
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monoamine Oxidase

Share to Polymorphism, Genetic

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Share to Serotonin Plasma Membrane Transport Proteins

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Source

Identifiers

PMID: 18405062

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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