Genetic variants of MAOB affect serotonin level and specific behavioral attributes to increase autism spectrum disorder (ASD) susceptibility in males.

doi:10.1016/j.pnpbp.2016.07.001

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Article

Genetic variants of MAOB affect serotonin level and specific behavioral attributes to increase autism spectrum disorder (ASD) susceptibility in males.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Nov 2016

Chakraborti Barnali, Verma Deepak, Karmakar Arijit, Jaiswal Preeti, Sanyal Aritrika, Paul Debarshi, Sinha Swagata, Singh Asem Surindro, Guhathakurta Subhrangshu, Roychowdhury Anirban, Panda Chinmoy Kumar, Ghosh Saurabh, Mohanakumar Kochupurackal P, Mukhophadhyay Kanchan, Rajamma Usha

Abstract excerpt

Serotonergic system participates in various developmental processes and modulation of behaviour. Autism Spectrum Disorder (ASD) is characterized by a range of behavioral symptoms scaling from mild to severe. Abnormal 5-HT synthesis and signalling, platelet hyperserotonemia and amelioration of repetitive behaviours by SSRI are some of the key findings, which reinforced the hypothesis that serotonergic genes might...

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Identifiers

PMID: 27381555
DOI: 10.1016/j.pnpbp.2016.07.001

Genes

MAOB
MAOA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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