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Article

PTEN regulates phospholipase D and phospholipase C.

Human molecular genetics - 15 May 2007

Alvarez-Breckenridge Christopher A, Waite Kristin A, Eng Charis

Abstract excerpt

PTEN is an ubiquitously expressed tumor suppressor which plays a prominent role in the pathogenesis of many types of sporadic solid tumors, including breast cancer, as well as hematologic malignancies. Germline PTEN mutations cause 85% of Cowden syndrome (CS), characterized by a high risk of brea...

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Source

Identifiers

PMID: 17405772
DOI: 10.1093/hmg/ddm063

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17405772-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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