Distinct oxidoresistance phenotype of human T47D cells transfected by rat glutathione S-transferase Yc expression vectors.

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Article

Distinct oxidoresistance phenotype of human T47D cells transfected by rat glutathione S-transferase Yc expression vectors.

The Journal of biological chemistry - 25 Feb 1992

Lavoie L, Tremblay A, Mirault M E

Abstract excerpt

We have investigated the role of a glutathione S-transferase (GST) with inherent peroxidase activity in the cellular defense against lipid peroxidation and free radical-mediated oxidative damage. Stable transfectants of human T47D cells were generated which express recombinant rat GST-Yc from a human cytomegalovirus promoter-based expression vector. Among several GST-Yc transfectants characterized, two of them...

Topics

Animals
Antioxidants
Benzene Derivatives
Cell Cycle
Cell Line
DNA
Electrophoresis, Polyacrylamide Gel
Free Radicals
Genetic Vectors
Glutathione Peroxidase
Glutathione Transferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Lipid Peroxidation

Phenotype

Rats

Recombinant Proteins

Rose Bengal

Thymidine

Source

Open in PubMed

Identifiers

PMID: 1740415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1740415-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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