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Article

c-Met is essential for wound healing in the skin.

The Journal of cell biology - 9 Apr 2007

Chmielowiec Jolanta, Borowiak Malgorzata, Morkel Markus, Stradal Theresia, Munz Barbara, Werner Sabine, Wehland Jürgen, Birchmeier Carmen, Birchmeier Walter

Abstract excerpt

Wound healing of the skin is a crucial regenerative process in adult mammals. We examined wound healing in conditional mutant mice, in which the c-Met gene that encodes the receptor of hepatocyte growth factor/scatter factor was mutated in the epidermis by cre recombinase. c-Met-deficient keratinocytes were unable to contribute to the reepithelialization of skin wounds. In conditional c-Met mutant mice, wound...

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Identifiers

PMID: 17403932
DOI: 10.1083/jcb.200701086
PMCID: PMC2064119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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