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Article

Met provides essential signals for liver regeneration.

Proceedings of the National Academy of Sciences of the United States of America - 20 Jul 2004

Borowiak Malgorzata, Garratt Alistair N, Wüstefeld Torsten, Strehle Michael, Trautwein Christian, Birchmeier Carmen

Abstract excerpt

Genetic analysis in mice has demonstrated a crucial role of the Met tyrosine kinase receptor and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), in development of the liver, muscle, and placenta. Here, we use conditional mutagenesis in mice to analyze the function of Met during liver regeneration, using the Mx-cre transgene to introduce the mutation in the adult. After partial hepatectomy in mice...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15249655
DOI: 10.1073/pnas.0403412101
PMCID: PMC490025

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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