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Article

C-Met Autocrine Activation Induces Development Of Malignant Melanoma And Acquisition Of The Metastatic Phenotype

1 Jan 1998

Abstract excerpt

The molecular and genetic events that contribute to the genesis and progression of cutaneous malignant melanoma, a complex and aggressive disease with a high propensity for metastasis, are poorly understood due in large part to the dearth of relevant experimental animal models. Here we used transgenic mice ectopically expressing hepatocyte growth factor/scatter factor (HGF/SF) to show that the Met signaling...

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Identifiers

PMID: 9823327
DOI: 10.5281/zenodo.894795

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