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Article

RNA interference against hepatitis B virus with endoribonuclease-prepared siRNA despite of the target sequence variations.

Virus research - 1 Jun 2007

Tan Chang, Xuan Baoqin, Hong Jie, Dai Zhaoyun, Hao Ruixin, Li Zhengwu, Huang Weida

Abstract excerpt

RNA interference (RNAi) has proven to be very powerful in inhibiting hepatitis B virus (HBV) replication by cell culture and mouse model studies. We have previously reported that endoribonuclease-prepared short interfering RNAs (esiRNAs) were able to inhibit HBV replication more efficiently than synthesized siRNAs. Here we tested the hypothesis that esiRNAs are able to inhibit gene expression with limited...

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Identifiers

PMID: 17399837
DOI: 10.1016/j.virusres.2007.02.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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