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Article

Optimized tandem amiRNA mediates stronger inhibitory effects on hepatitis B virus infection.

Journal of gastrointestinal and liver diseases : JGLD - 1 Sept 2011

Pu Chunwen, Wang Lifen, Miao Xiaohui, Zhang Yong, Jiang Chunmeng, Liu Wei, Sun Weixiang, Gao Qingwei

Abstract excerpt

BACKGROUND AND AIMS: RNA interference (RNAi) has emerged as a potential new approach against hepatitis B virus (HBV) infection but unfortunately it also selects resistant virus mutants. In this study we combined the advantages of artificial micro RNAs (amiRNAs) reported previously with the purpose of constructing a more practical amiRNA with high inhibition effects against HBV. METHOD: Aiming at conserved sites,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21961095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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