Article
Thrombopoietic cells and the bone marrow vascular niche.
Annals of the New York Academy of Sciences - 1 Jun 2007
Kopp H G, Rafii S
Abstract excerpt
Megakaryocytes and platelets have been known to secrete angiogenic growth factors for a long time. However, there is little in vivo data on the regulation of angiogenesis by thrombopoietic cells. Both megakaryocytes and platelets are known to carry and release a multitude of both pro- and antiangiogenic mediators. Thus, it remained unknown how the "angiogenic phenotype" of thrombopoietic cells would be...
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