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Intra-bone marrow diversity of endothelial cells and its impact on hematopoietic stem cell development and maintenance

26 May 2025

Abstract excerpt

In addition to supplying oxygen and nutrients, blood vessels secrete paracrine molecules known as angiocrine factors to promote tissue homeostasis and repair. The bone marrow (BM) vasculature in long bones has differing properties between the diaphysis, metaphysis, and epiphysis in terms of its morphology, plasticity, perivascular cellular components, and angiocrine profiles. Blood vessel formation is linked with...

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PMID: 40436201
DOI: 10.1016/j.exphem.2025.104817

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