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Article

Platelet-derived factor V promotes angiogenesis in a mouse hind limb ischemia model.

Journal of vascular surgery - 1 Apr 2017

Yang Yan, Xiao Lamei, Chen Ni, Li Yongjie, Deng Xin, Wang Liqun, Sun Hongmin, Wu Jianbo

Abstract excerpt

OBJECTIVE: Coagulation factor V (FV) is distributed in plasma and platelet pools, which are distinguished by physical and functional differences. FV has been extensively studied for its roles in coagulation. The roles of FV in other physiologic pathways remain understudied. METHODS: Hind limb ischemia was produced in transgenic mice by femoral artery ligation, with different levels of FV gene expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27237401
DOI: 10.1016/j.jvs.2016.03.453

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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