Article
Relationship between human leucocyte antigen class I and class II and chronic idiopathic urticaria associated with aspirin and/or NSAIDs hypersensitivity.
Mediators of inflammation - 1 Jan 2006
Pacor Maria Luisa, Di Lorenzo Gabriele, Mansueto Pasquale, Martinelli Nicola, Esposito-Pellitteri Maria, Pradella Paola, Uxa Laura, Di Fede Gaetana, Rini GiovamBattista, Corrocher Roberto
Abstract excerpt
BACKGROUND: HLA genes play a role in the predisposition of several diseases. The aim was to analyze the prevalence of HLA class I phenotypes and HLA-DRB1* genotype in patients with CIU associated with ASA and NSAIDs hypersensitivity (AICU). METHODS: 69 patients with AICU, and 200 healthy subjects. RESULTS: Subjects with HLA-B44 and HLA-Cw5 antigens were more represented in patients with AICU than in control...
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