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Article

Interleukin-1 alpha genotype and outcome of unrelated donor haematopoietic stem cell transplantation for chronic myeloid leukaemia.

British journal of haematology - 1 Apr 2007

Mehta Parinda A, Eapen Mary, Klein John P, Gandham Sharavi, Elliott James, Zamzow Tiffany, Combs Michelle, Aplenc Richard, MacMillan Margaret L, Weisdorf Daniel J, Petersdorf Effie, Davies Stella M

Abstract excerpt

Interleukin-1 alpha (IL-1alpha) is a pro-inflammatory cytokine that is implicated in the initiation/maintenance of graft-versus-host disease (GVHD) and the immune response to infection. A cytosine (C) to thymine (T) transition at position -889 is believed to influence gene transcription. A previous single institution study showed that the presence of at least one IL1A T allele in the donor was associated with...

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Identifiers

PMID: 17391495
DOI: 10.1111/j.1365-2141.2007.06552.x
PMCID: PMC2914502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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