Article
Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia.
Haematologica - 1 Jun 2010
Dickinson Anne M, Pearce Kim F, Norden Jean, O'Brien Stephen G, Holler Ernst, Bickeböller Heike, Balavarca Yesilda, Rocha Vanderson, Kolb Hans-Jochem, Hromadnikova Ilona, Sedlacek Petr, Niederwieser Dietger, Brand Ronald, Ruutu Tapani, Apperley Jane, Szydlo Richard, Goulmy Els, Siegert Wolfgang, de Witte Theo, Gratwohl Alois
Abstract excerpt
BACKGROUND: Non-HLA gene polymorphisms have been shown to influence outcome after allogeneic hematopoietic stem cell transplantation. Results were derived from heterogeneous, small populations and their value remains a matter of debate. DESIGN AND METHODS: In this study, we assessed the effect of single nucleotide polymorphisms in genes for interleukin 1 receptor antagonist (IL1RN), interleukin 4 (IL4),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.