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Article

Polymorphisms of interleukin‐1α constitute independent risk factors for chronic graft‐versus‐host disease after allogeneic bone marrow transplantation

21 Aug 2003

Abstract excerpt

The interleukin-1 (IL-1) family of cytokines is widely involved in inflammatory processes and diseases with an inflammatory component. Polymorphisms of the IL-1alpha, IL-1beta and IL-1Ra genes have been implicated in a number of autoimmune or inflammatory conditions, with polymorphism of the IL-1Ra gene showing association with severity of graft-versus-host disease (GVHD) after allogeneic bone marrow...

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PMID: 12930389
DOI: 10.1046/j.1365-2141.2003.04510.x

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