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Article

Association of functional heme oxygenase-1 gene promoter polymorphism with renal transplantation outcomes.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Apr 2007

Courtney A E, McNamee P T, Middleton D, Heggarty S, Patterson C C, Maxwell A P

Abstract excerpt

Heme oxygenase-1 (HO-1) is a cytoprotective molecule and increased expression in experimental transplant models correlates with reduced graft injury. A functional dinucleotide repeat (GT)(n) polymorphism, within the HO-1 promoter, regulates gene expression; a short number of repeats (S-allele <25) increases transcription. The role of this HO-1 gene promoter polymorphism on renal transplant outcomes was assessed....

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Identifiers

PMID: 17391133
DOI: 10.1111/j.1600-6143.2006.01726.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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