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Donor heme oxygenase-1 genotype is associated with renal allograft function.

Transplantation - 27 Feb 2004

Exner Markus, Böhmig Georg A, Schillinger Martin, Regele Heinz, Watschinger Bruno, Hörl Walter H, Raith Marianne, Mannhalter Christine, Wagner Oswald F

Abstract excerpt

BACKGROUND: The heme oxygenase (HO) isoenzyme HO-1 has recently been suggested to protect transplants from ischemia/reperfusion and immunologic injury. Inducibility of this enzyme is modulated by a (GT)n dinucleotide length polymorphism in the HO-1 gene promoter. Short (class S) repeats are associated with greater up-regulation of HO-1 than are long repeats. In the present study we investigated the impact of the...

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PMID: 15084931
DOI: 10.1097/01.tp.0000113467.36269.f8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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