Article
The impact of endothelial nitric oxide synthase polymorphisms on long-term renal allograft outcome.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Jun 2003
Shenker Natalie S, Haldar Neil A, Reilly John-Joe, Bunce Mike, Welsh Ken I, Marshall Sara E
Abstract excerpt
A major manifestation of chronic allograft failure (CAF) is the accelerated onset of atherosclerotic lesions within the graft. Polymorphisms in the endothelial nitric oxide synthase (eNOS) gene have been implicated in the pathogenesis of native atherosclerosis. This study tested the hypothesis that polymorphisms in eNOS are associated with susceptibility to CAF after cadaveric renal transplantation. The patient...
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