Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional polymorphism of thymidylate synthase, but not of the COMT and IL-1B genes, is associated with breast cancer.

Journal of clinical laboratory analysis - 1 Jan 2007

Akisik Elif, Dalay Nejat

Abstract excerpt

Polymorphic variations may affect the rate of gene transcription, the stability of the mRNA, or the quantity and activity of the resulting protein. In this study we evaluated the association between the interleukin-1B C-31T, catechol-O-methyltransferase Val158Met, and thymidylate synthase (TS) 14...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Catechol O-Methyltransferase
Share to DNA Fingerprinting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Interleukin-1beta

Share to Polymorphism, Restriction Fragment Length

Share to Thymidylate Synthase

Share to Turkey

Source

Open in PubMed Open full text

Identifiers

PMID: 17385677
DOI: 10.1002/jcla.20139
PMCID: PMC6649245

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17385677-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional polymorphism of thymidylate synthase, but not of the COMT and IL-1B genes, is associated with breast cancer.PMID 17385677Read ↗

Lack of association between catechol-O-methyltransferase Val108/158Met polymorphism and breast cancer risk: a meta-analysis of 25,627 cases and 34,222 controls.Semantic proximity Read ↗

Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in CYP1B1 and COMT genes with breast cancer susceptibility in Indian women.Semantic proximity Read ↗

COMT Val158Met polymorphism and breast cancer risk: evidence from 26 case-control studies.Semantic proximity Read ↗

Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer risk: a case control study in Syria.Semantic proximity Read ↗

Association between the COMT Val158Met polymorphism and breast cancer risk: a meta-analysis of 30,199 cases and 38,922 controls.Semantic proximity Read ↗

Catechol-O-Methyltransferase (COMT) gene polymorphism and breast cancer risk in young women.Semantic proximity Read ↗

Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer risk.Semantic proximity Read ↗

Catechol-O-methyltransferase Val158Met polymorphism and breast cancer risk in Asian population.Semantic proximity Read ↗

Association of COMT haplotypes and breast cancer risk in caucasian women.Semantic proximity Read ↗

Comprehensive assessment of genetic variation of catechol-O-methyltransferase and breast cancer risk.Semantic proximity Read ↗

Association between polymorphisms in the thymidylate synthase gene and risk of breast cancer in a Mexican population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.