Article
Role of Müller cells in cone mosaic rearrangement in a rat model of retinitis pigmentosa.
Glia - 1 Jul 2011
Lee Eun-Jin, Ji Yerina, Zhu Colleen L, Grzywacz Norberto M
Abstract excerpt
Retinitis pigmentosa (RP) is a type of inherited retinal degenerative disease, which leads to blindness. The primary pathological event of this disease is the death of rods because of genetic mutations. The S334ter-line-3 rat is a transgenic model developed to express a rhodopsin mutation similar to that found in RP. In this study, the rod's death triggered are organization of the cone mosaic into an orderly...
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