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Article

Quantitation of RHD by real-time polymerase chain reaction for determination of RHD zygosity and RHD mosaicism/chimerism: an evaluation of four quantitative methods.

Transfusion - 1 Apr 2007

Krog Grethe Risum, Clausen Frederik Banch, Dziegiel Morten Hanefeld

Abstract excerpt

BACKGROUND: Determination of RHD zygosity of the spouse is crucial in preconception counseling of families with history of hemolytic disease of the fetus and newborn caused by anti-D. RHD zygosity can be determined by quantitative real-time polymerase chain reaction (PCR) basically by determining RHD dosage, and this feature is relevant in investigating RHD mosaicism and chimerism. STUDY DESIGN AND METHODS:...

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Source

Identifiers

PMID: 17381631
DOI: 10.1111/j.1537-2995.2007.01175.x

Genes

RHD
GAPDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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