Article
The impact of donor and recipient KIR genes and KIR ligands on the occurrence of acute graft-versus-host disease and graft survival after HLA-identical sibling hematopoietic stem cell transplantation
Turkish journal of medical sciences - 16 Aug 2018
Hoseinian Seyed Ahmad, Jafari Davood, Mahmoodi Mehdi, Alimoghaddam Kamran, Ostadali Mohammadreza, Talebzadeh Bonakdar Azita, Foma Arron Munggela, Yekaninejad Mir Saeed, Amirzargar Ali Akbar
Abstract excerpt
Background/aim: After allogeneic hematopoietic stem cell transplantation (allo-HSCT), donor natural killer (NK) cells trigger alloreactions against potential recipient cells by their killer immunoglobulin-like receptors (KIRs). This study investigated whether KIR/HLA genotypes and KIR haplotypes of donors and recipients exhibit a critical function in the prevalence of acute...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.