Article
Effects of donor killer-cell immunoglobulin-like receptor genotypes on clinical outcome after allogeneic hematopoietic stem cell transplantation-a systematic review and meta-analysis.
Frontiers in immunology - 1 Jan 2026
Huang Yarui, Li Qingrong, Xu Xin, Li Ju, Zhu Yan, Luo Chengxin, Xu Jiegang, Liu Jiaming, Zhang Jianmin, Wang Ping, Tan Ya, Ding Yaqun, Xu Shuangnian, Chen Run, Wei Ling
Abstract excerpt
Purposed: Natural Killer cell kinetics and Killer-cell immunoglobulin-like receptors (KIRs) are increasingly recognized for their role during allogeneic hematopoietic stem cell transplantation (allo-HSCT), but the prognostic impact of donor KIR haplotype configurations on patient survival remains controversial. To clarify this relationship, we conducted a systematic review and meta-analysis evaluating the impact...
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