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Article

Real-time multiplex PCR assay for genotyping of three apolipoprotein E alleles and two choline acetyltransferase alleles with three hybridization probes.

Clinical chemistry and laboratory medicine - 1 Jan 2007

Park Hyung-Doo, Park Kyoung Un, Kim Ki-Woong, Song Junghan, Chang Ho Eun, Heo Se Ran, Lee Hyun Jung, Kim Jin Q

Abstract excerpt

BACKGROUND: Apolipoprotein E (APOE) and choline acetyltransferase (ChAT) have been suggested as candidate genes for determining the risk of late-onset Alzheimer's disease. The aim of this study was to simultaneously detect polymorphisms in codons 112 and 158 of APOE and codon 2 of ChAT by hybridization probe multiplexing. METHODS: The decrease in fluorescence emitted by LC-Red 610, LC-Red 640, and LC-Red 705...

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Source

Identifiers

PMID: 17378730
DOI: 10.1515/CCLM.2007.075

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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