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Article

Arginine-based PNA microarrays for APOE genotyping.

Molecular bioSystems - 1 Nov 2009

Calabretta Alessandro, Tedeschi Tullia, Di Cola Gabriella, Corradini Roberto, Sforza Stefano, Marchelli Rosangela

Abstract excerpt

Four modified PNAs containing one chiral monomer bearing two arginine-derived side chains, with the correct configuration for specific and stable DNA binding, were synthesized, complementary to two DNA tracts in the APOE gene containing SNPs related to the insurgence of Alzheimer's disease. PNA binding performances were first tested in solution against complementary and mismatched oligonucleotides by measuring...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19823748
DOI: 10.1039/b909912n

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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