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Article

Color multiplexing hybridization probes using the apolipoprotein E locus as a model system for genotyping.

Analytical biochemistry - 10 Sept 1999

Bernard P S, Pritham G H, Wittwer C T

Abstract excerpt

Fluorescent hybridization probes were multiplexed for color genotyping of the apolipoprotein E locus using model oligonucleotide targets. Fluorescence resonance energy transfer was observed during adjacent hybridization of 3'-fluorescein-labeled "donor" probes paired with 5'-labeled "acceptor" probes with different emission spectra reporting at codons 112 and 158. The acceptor dyes emitted at either 640 nm...

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Identifiers

PMID: 10469493
DOI: 10.1006/abio.1999.4217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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