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Article

Real time PCR assay with fluorescent hybridization probes for genotyping intronic polymorphism in presenilin-1 gene.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2006

Rodriguez-Manotas Miguel, Amorin-Diaz Manuel, Viñals-Bellido Inmaculada, Cabezas-Herrera Juan, Martinez-Hernandez Pedro, Cañizares-Hernandez Francisco

Abstract excerpt

BACKGROUND: Identification of all susceptibility loci for Alzheimer's disease has been a major goal in resolving the pathogenesis of this disease. METHODS: A PCR assay with fluorescently labeled oligonucleotide hybrinization probes with subsequent fluorescent probe melting point analysis was developed. RESULTS: Allelic discrimination of intronic polymorphism of presenilin-1 gene and the restriction fragment...

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Identifiers

PMID: 16139258
DOI: 10.1016/j.cccn.2005.06.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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