Article
Enhanced capillary electrophoretic screening of Alzheimer based on direct apolipoprotein E genotyping and one-step multiplex PCR.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 1 Jan 2018
Woo Nain, Kim Su-Kang, Sun Yucheng, Kang Seong Ho
Abstract excerpt
Human apolipoprotein E (ApoE) is associated with high cholesterol levels, coronary artery disease, and especially Alzheimer's disease. In this study, we developed an ApoE genotyping and one-step multiplex polymerase chain reaction (PCR) based-capillary electrophoresis (CE) method for the enhanced diagnosis of Alzheimer's. The primer mixture of ApoE genes enabled the performance of direct one-step multiplex PCR...
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