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Article

Involvement of epidermal growth factor receptor and downstream molecules in bone and soft tissue tumors.

Human pathology - 1 Jun 2007

Dobashi Yoh, Suzuki Shioto, Sugawara Hisanori, Ooi Akishi

Abstract excerpt

Correlations among epidermal growth factor receptor (EGFR) gene amplification, mutation, and overexpression/activation of proteins were investigated in 39 cases of bone/soft tissue tumors (BSTTs). By immunohistochemistry, EGFR overexpression was found in 22.6% of sarcomas, but not in benign lesions. By immunoblotting, among sarcoma cases showing upregulation of EGFR, 47.4% showed EGFR activation. In 2 cases of...

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Source

Identifiers

PMID: 17376509
DOI: 10.1016/j.humpath.2006.12.005

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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