Article
Expression of receptor tyrosine kinases epidermal growth factor receptor and HER‐2/<i>neu</i> in synovial sarcoma
7 Jan 2005
Abstract excerpt
BACKGROUND: Synovial sarcomas are high-grade soft tissue neoplasms often characterized by a biphasic spindle and epithelioid cell morphology. The majority of synovial sarcomas harbor a specific chromosomal translocation in which the proximal portion of the SYT gene at chromosome 18q11 is fused to the distal portion of one of several duplicated SSX genes (most notably SSX1 and SSX2) at chromosome Xp11. SYT/SSX1...
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