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Article

Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2006

Bode Beata, Frigerio Simona, Behnke Silvia, Senn Belinda, Odermatt Bernhard, Zimmermann Dieter R, Moch Holger

Abstract excerpt

The prognosis of patients with synovial sarcomas is poor. New therapeutic strategies, such as target inhibition of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) with erlotinib and gefinitib, could be effective, because most synovial sarcomas overexpress this protein....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16514409
DOI: 10.1038/modpathol.3800560

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16514409-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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