Article
Altered editing in RNA editing adenosine deaminase ADAR2 gene transcripts of systemic lupus erythematosus T lymphocytes.
Immunology - 1 Jul 2007
Laxminarayana Dama, O'Rourke Kenneth S, Maas Stefan, Olorenshaw Irene
Abstract excerpt
Adenosine Deaminases that act on RNA (ADARs) edit gene transcripts through site-specific conversion of adenosine to inosine by hydrolytic deamination at C6 of the adenosine. ADAR2 gene transcripts are substrates for the ADAR1 and ADAR2 enzymes and their expression is regulated by editing at the -...
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