Article
Characterization of the COMMD1 (MURR1) mutation causing copper toxicosis in Bedlington terriers.
Animal genetics - 1 Dec 2005
Forman O P, Boursnell M E G, Dunmore B J, Stendall N, van den Sluis B, Fretwell N, Jones C, Wijmenga C, Rothuizen J, van Oost B A, Holmes N G, Binns M M, Jones P
Abstract excerpt
Copper toxicosis is an autosomal recessive disorder affecting Bedlington terriers, characterized by elevated liver copper levels and early death of affected dogs. Genetic linkage mapping studies initially identified linkage between the disease and the microsatellite marker C04107. Subsequently, t...
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