Article
Characterization of COMMD protein-protein interactions in NF-kappaB signalling.
The Biochemical journal - 15 Aug 2006
de Bie Prim, van de Sluis Bart, Burstein Ezra, Duran Karen J, Berger Ruud, Duckett Colin S, Wijmenga Cisca, Klomp Leo W J
Abstract excerpt
COMMD [copper metabolism gene MURR1 (mouse U2af1-rs1 region 1) domain] proteins constitute a recently identified family of NF-kappaB (nuclear factor kappaB)-inhibiting proteins, characterized by the presence of the COMM domain. In the present paper, we report detailed investigation of the role of this protein family, and specifically the role of the COMM domain, in NF-kappaB signalling through characterization of...
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